MI-CP151 was a stage 1b randomised, double-blind, placebo controlled, dose-escalation, multicentre review To guage various intravenous doses of sifalimumab, in Grownup patients with dermatomyositis or polymyositis (NCT00533091). Principal trial objectives ended up to evaluate the security and tolerability of sifalimumab in dermatomyositis or polymy
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An enzyme current on the brush border in the enterocytes, the lactase phlorizin hydrolase, releases the aglycone which will then enter the epithelial cells by passive diffusion due to its enhanced lipophilicity and its proximity into the enterocyte membrane. β-glucosidases also liberate cost-free aglycones which can be much more hydrophobic and po
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